Dr. Evelyn Evergreen was a brilliant neuroscientist specializing in the study of psychic phenomena. During an experiment involving a rare crystal with psychic properties, an unexpected energy surge transformed Evelyn into Psyren, imbuing her with psychic powers akin to those of an Espeon. Embracing her newfound abilities, Evelyn became Psyren, a superheroine dedicated to protecting the city from psychic threats and injustice.