Design a fusion artwork that merges Renaissance portraiture with futuristic cyberpunk aesthetics. The central figure should be a detailed, classical portrait with realistic textures and intricate clothing, enhanced with cyberpunk elements like neon tattoos, high-tech accessories, and holographic displays. The background should be a bustling, neon-lit cityscape, with towering skyscrapers and glowing advertisements. Use a high contrast between the warm, earthy tones of the portrait and the cool, vibrant neon colors of the city. Incorporate dynamic lighting with reflections and lens flares to emphasize the high-tech setting. The artwork should be digital, with a polished, high-resolution finish.