The Binding of Isaac, indie game, roguelike, top-down shooter, pixel art, series progression, chronological release, The Binding of Isaac (2011), Wrath of the Lamb expansion, Rebirth (2014), Afterbirth expansion, Afterbirth+ expansion, Repentance expansion, evolving gameplay, enhanced graphics, additional content, Isaac character, crying attack, dungeon crawler, monsters, bosses, dark humor, religious themes, procedurally generated levels, collectible items, power-ups, multiple endings, cult following, atmospheric lighting, eerie soundtrack, challenging difficulty, Steam platform, console versions, cult classic, Edmund McMillen, Florian Himsl.